The US witnessed a 21 percent increase in people dying from drug overdoses in 2016. The increase is "largely due to a rise in deaths associated with pharmaceutical opioids, including fentanyl and fentanyl analogues."
But the crisis in the US has spread beyond the country's borders, with the UN saying: "We need to raise the alarm about addiction to tramadol, rates of which are soaring in parts of Africa."
On Monday, the White House issued a report with similar findings on Colombia's cocaine production surge. US President Donald Trump has threatened to decertify Colombia as a partner in Washington's "War on Drugs" if it doesn't curb the upward trend.
"President Trump's message to Colombia is clear: The record growth in cocaine production must be reversed," said Jim Carroll, deputy director for the US drug policy office.