The merger of the two giant companies will create the largest agricultural conglomerate in the world - but environmental activists strongly oppose it.
Despite a pledge not to have lay-offs until 2025, a "significant number" of the job cuts at Bayer will be in Germany. More than 1,000 employees in the western city of Wuppertal came out to protest a plant closure.
Pharmaceutical company Bayer is heading for a restructuring that would see it shed 12,000 jobs in various countries, the firm's representatives said. The German giant took over US-based Monsanto earlier this year.
UK drugmaker Glaxo wants to split in two businesses, after agreeing with its US rival Pfizer to form a consumer health joint venture that will become the world's biggest provider of non-prescription drugs.
Germany's giant chemicals conglomerate, Bayer, has completed its takeover of US-based Monsanto. The Monsanto name, long touted by activists as a byword for corporate evil, will disappear. So now it's all good, right?
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